L-Leucine

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L-Leucine: natural ingredient of Lastevolution

Leucine is an essential amino acid for the human body that not being able to synthesize, needs a constant supply with diet. As all the amino acids, leucine is present especially in food derived from animal protein, but unlike other is also found in legumes and cereals.

Leucine is essential for growth and muscular endurance, promotes protein synthesis and supports the metabolism of fasting possessing ketogenic activity.

Together with two other essential amino acids, referred to as isoleucine and valine is an amino acid especially used in sports, where it is known by the acronym BCAA (brain chain aminoacids) or branched-chain amino acids.

Leucine, isoleucine and valine are about 20% of the amino acids assimilated by feeding and are particularly concentrated within the muscle. The branched chain amino acids are an important source of alternative energy at which the body turns significantly during intense and prolonged effort.

The administration of the branched acids is commonly known as one of the most valid both for energy which supplements that for being carriers of valuable benefits.
The set of branched amino acids is composed of L-isoleucine, L-leucine and L-valine, that is to say 3 essential amino acids that provide about 30/40% of all muscle proteins.

Have been developed many scientific works which document the major activity of leucine, especially as regards the recovery of energy and the stimulus to the endogenous secretion of growth hormone and insulin.
The peculiarity of such amino acids is due to their ability to be metabolized directly into muscle tissue and the muscle itself, so their metabolism does not involve the liver.

 

L-Leucine: natural ingredient of Lastevolution

Leucine Synthesis and protein attachment

Numerous studies have documented that to achieve a balanced nitrogen balance is necessary to use a portion of proteins that include the amino acid leucine.

Protein synthesis is the creation of new proteins of skeletal muscle. When protein synthesis is carried out on a large scale is known as hypertrophy of skeletal muscle, ie the increase in the unit transverse muscle and is the process by which our muscles become larger.
Supplementation rich in amino acids, especially of leucine, rebalances muscle protein synthesis after intense physical activity.

Doing resistance training, it affects protein turnover in skeletal muscle reducing the rate of protein synthesis and increasing the level of muscle catabolism.

In addition to isoleucine and valine, L-leucine is one of the three branched chain amino acids (BCAA) and with respect to the stimulation of protein synthesis in muscles, has an effect of 10 times greater than any other amino acid.

Leucine protein synthesis and MTOR

Leucine activates a very important mechanism in our bodies and in the anabolic pathway: it is MTOR (Mammali-
an Target Of Ripamycin), which is a very important stabilizing protein synthesis.

The MTOR is put into action when levels of ATP (adenosine triphosphate) are high and it is essential with regard to hypertrophy of the muscles.