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In Bacillus subtilis, and in Colostrum, the active ingredients in Genesis, was discovered also Relaxin.
Relaxin is naturally produced in all of us. It is a relatively low molecular weight protein. Relaxin is closely linked to another important hormone in our body, insulin.

We have relaxin receptors throughout our autonomic nervous system and in the brain, in smooth muscles (including blood vessels, arteries and digestive tract), skin and connective tissue. Perhaps its main role is to regulate the synthesis and maintenance of collagen, our primary connective tissue protein. Every part of our body and virtually every body function is therefore affected or potentially affected by relaxin. Muscles / tendons and ligament integrity, nerve conductivity, regular heartbeat and even bone health are all positively influenced by relaxin.

Relaxin is pro-angiogenic, stimulating the growth of new blood vessels in selective target tissues such as the uterine endometrial lining (Dallenbach et al., 1966) and wounded ischemic sites (Unemori et al.). Relaxin stimulates expression of vascular endothelial growth factor (VEGF) and fibroblast growth factor (bFGF), potent angiogenic factors that can synergistically stimulate the formation of new blood vessels (Asahara et al., 1995) in cells Endometrial stromals (Unemori et al., 1996) and heart cells (Lewis et al., Submitted).

La Realxina stimola la vasodilatazione del letto vascolare. Relaxina provoca vasodilatazione dall’attivazione del sottotipo del recettore dell'endotelina B e la stimolazione di ossido nitrico (Danielson et al., 2000) (Bani-Sacchi et al, 1995; Danielson et al., 1999). Relaxina inibisce anche gli effetti vasocostrittori dell’angiotensina II (Danielson et al, 1999;.. Massicote et al, 1989).

Realxin stimulates vasodilatation of the vascular bed. Relaxin causes vasodilatation by activating the subtype of the endothelin B receptor and the stimulation of nitric oxide (Danielson et al., 2000) (Bani-Sacchi et al, 1995; Danielson et al., 1999). Relaxin also inhibits the vasoconstrictor effects of angiotensin II (Danielson et al., 1999; Massicote et al., 1989).

There is evidence that stimulates the production of atrial natriuretic peptide (Toth et al., 1996). Relaxation is anti-fibrotic, favoring the degeneration of the connective tissue, especially in fibrous conditions. Relaxin acts as an anti-fibrous agent with three distinct routes and additives: Relaxin directly reduces collagen production; Increases the expression of collagenase, the enzyme that degrades collagen and reduces the production of the best known collagenase inhibitor such as TIMP (Strutz et al., 1999; McDonald et al., 1999; Williams et al., 1999; Unemori et al., 1992 Unemori et al., 1990).

Relaxin is valuable in the treatment of atherosclerosis, stroke and, in general, heart disease, and not only because it is involved in many other pathologies and in regulating the functioning of so many biological mechanisms so as to significantly affect the longevity of people.
Relaxin, the researchers say, "can truly be an innovative therapy for cardiovascular disease, as it induces microvascular dilatation, increases blood flow, inhibits platelet and neoplasm formation."


Probable source of greater longevity in women, hormone Relaxin, naturally produced during pregnancy, now promises epochal innovations in the prevention and therapy of cardiovascular diseases (arteriosclerosis, heart disease, stroke), 1st cause of death and disability. In its own way prolongs life. In analogy with the famous Higgs Bosone, it is therefore called by some of God's hormones.

The University of Vermont ensures that Relaxin has regenerating effects on the cellular structure (parenchyma) of brain microarrays, thus acting on age-related vascular diseases or hypertension, which can cause stroke, white matter injury, dementia. There are three main mechanisms through which relaxin acts on the vascular system:

  • Immediate vasodilatation - mainly due to the cells of the vessels themselves, which stimulate the release of nitric oxide
  • Long-term revascularization / reperfusion - this effect is mostly due to two phenomena: vascular stimulation of the production of angiogenic factors (such as VEGF) and the remodeling of collagen fibers Of the connective tissue of the blood vessels and their surroundings.
  • Antithrombotic effects - are useful in the prevention and treatment of vascular diseases, and are largely due to the inhibition of blood platelets, an anticoagulant process also mediated by the release of nitric oxide.
Relaxin promotes the release of nitric oxide and antagonizes the effects of endothelin by causing peripheral vasodilation, cardiac output and renal function.It also has antiplatelet action and antifibrotic favorable on cardiovascular function. In addition to being a powerful vasodilator, it improves angiogenesis.
Its receptors are mainly in the heart, connective tissue and central nervous system. From here all recent scientific confirmations about cardiovascular disease and those of new address on fibromyalgia and scleroderma.

The results obtained so far in in vivo and in vitro experiments and also in humans demonstrate the great therapeutic potential of this hormone capable of inducing surprising improvements in diseases of various organs and apparatus, and in particular in ischemic vascular diseases such as cardiac infarction, Stroke, limbs of the limbs, with even regenerating effects of the injured tissues.

Indeed, Relaxina has confirmed its capacity for vasodilation, encouraging increased oxygenation of the brain, but also the ability to influence brain activity, perhaps even by promoting the plasticity of the brain itself.

Some studies have shown how Relaxin can favor the appearance of "arterial neoformations": it not only protects blood vessels but helps to create new ones in case of insufficient circulation.

Based on all the experimental results we can say that Relaxin is probably the most important of the vascular hormones. It has full effectiveness in primary prevention: as a vasodilator removes the risk of hypertension and plaques; Is a valid secondary prevention tool, as has been demonstrated in stroke or other atherosclerosis studies; is a valid acute phase therapy, as in the case of a heart attack and heart failure. 
Relaxin studies relate to many other aspects of the human body's function: I remember that in the male Relaxin is also produced by the prostate and is present in the human seminal fluid, hence a hypothesis about the incidence of fertility; as a powerful vasodilator through the production of nitric oxide can have an effect or synergy with the viagra-type drugs.