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you are visiting: home » products » Mycream Men » composition » caffeine (Pag. 1) » caffeine (Pag. 5)
Caffeine - Pag. 5

Mycream Men:

Caffeine: natural ingredient of Mycream Men

Cosmetic activity of caffeine in Mycream Men

Since the formation of excess fat is related to circulatory problems with leakage of fluid into the interstices and exclusion of adipocytes with blocking metabolic exchanges, it is appropriate to take action through a draining and detoxifying action to dissolve the collagen fibers that inhibit the fat cells.

It is for this reason that it may be useful the cosmetic application of caffeine for its capacity to promote drainage and removal of stagnant fluids, even if the primary action of the molecule is to stimulate the mobility of the fatty acids in adipose tissue.

Caffeine stimulates the activity of AMPcThe adipo-lytic activity is recurrent and cyclical in normal tissue, with a periodicity of approximately fifteen days. It occurs through the interventi-
on of hormones such as glucagon and ATCH that stimulate adenylate cyclase to convert ATP into cAMP which, with hormone-like action, stimulates phosphorylation using the activation of lipase adipo-lytic. This allows the hydrolysis of triglycerides in diglycerides that are in a second time separated into fatty acids and then removed.

Caffeine stimulate the activity of cAMP blocking phosphodie-
sterase the enzyme that degrades cAMP and prevents lipolysis. The local use of caffeine causes no contraindica-
tions, at the present
, since the transdermal absorption does not show blood concentrations likely to develop systemic consequences.
The topical use of caffeine in the cosmetics sector is suitable for the treatment of localized adiposities and is motivated to the catabolic effects on the adipocytes.

Caffeine has ideal properties to be assimilated for topical application, thanks to a good “HLB” (Hydrophylic Lipophylic--Balance) that does not permit the propagation through the epidermis.
Different formulations have been developed to further optimize the kinetics of absorption, including additional active ingredients including limonene, or using the inclusion of the caffeine in the liposomes.

Absorption is to bring the amount until the to adipocytes on which exhibits the specific catabolic activities removing themselves from admission in the blood vessels and not leading to peak blood such as to stimulate systemic results.

The absorption of active ingredients through the skin is affected by the level of skin hydrationIt is useful to recall that the absorption of active ingredients through the skin is conditioned by the level of hydration as the epidermal lipid component is the main vector for the dissolution of the substances applied.
A change or reduction, in the process wear and tear typical of the dermal absorption can lead to reducing the absorption. For this reason it is appropriate a precautionary nutrition and hydration epithelial products with anti-aging specific for the parts to be treated, in order to optimize the validity of the aesthetic care.

A special new use of caffeine provide the use as a sunscreen for the UVC radiation, thanks to the absorption of the electromagnetic spectrum. Protecting power of these emissions highly energetic, that if perpetrated for a long time can develop neoplasms may be borne by the epidermis, is a factor of current and confirmed interest in order to prevent adverse effects determined by the thinning of the ozone layer.

Also in the prophylaxis optic of effects caused by ultraviolet radiations, studies in vitro have shown that caffeine plays protective action against the UVB rays, reducing the neoplastic potentialities.

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