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you are visiting: home » products » Mycream Men » composition » caffeine (Pag. 1) » caffeine (Pag. 4)
Caffeine - Pag. 4

Mycream Men:

Caffeine: natural ingredient of Mycream Men

Activity of caffeine (Continued ...)

Caffeine and paraxantina can influence the blood pressure As they can increase the systemic vascular resistance through the block of the adenosine receptors with contractile effect. For every cup of coffee, systolic blood pressure increases of 0.8 mmHg., while the diastolic by 0.5 mmHg.

The caffeine is used against migraine to facilitate the absorption and increase the activity of ergotamine, which induces vasoconstriction and reduced blood flow extracrani-
al, affecting the serotonin receptors.

Another effect of the blocking activity of adenosine is the analgesic effect. Caffeine is able to control the release of mediators pain symptoms caused by adenosine at the level of nerve terminals and is able to activate the pathways of adrenaline that implement suppressive action on the pain and stimulate the nervous system by reducing the affective component in processing stimulation.
Caffeine stimulates acid secretion in the stomach by the action on H2 receptors, and for this reason should be avoided in individuals predisposed to ulcers.

Side effects and contraindications

Excessive intake of caffeine causes side effects and contraindicationsWith regard to the acute toxicity, can be identified in the short term outcomes after assumptions bet-
ween 1 and 5 g. of caffeinethat could cause plasma concentrati-
ons above 80 mg/ml.
Symptoms of intoxication show up with assumptions around 250 mg.while higher doses (650 mg.), cause the syndrome of the “coffeinism”, characte-
rized by anxiety, agitation and sleep disorders in very similar to anxiety stress.

This type of anxious manifestation began attract attention already at concentrations of 30 mg. / Ml. a result of assumptions of 1 g. of caffeine. The continued recruitment of small quantities of caffeine found no toxic effects.
In addition, subjects with overt hypertension have not manifested variations connectable to the use of coffee, or have been found increased danger of myocardial infarction.

Caffeine does not appear affect the course of gestation or birth weight, or induce genetic abnormalities. Situations of chronic toxicity can occur in case of prolonged use of coffee in association with cigarette smoking or alcohol, as these will vary the pharmacokinetics of caffeine. Therefore it is difficult to determine whether the consequences are caused solely by the xanthine base or from other causes.

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