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you are visiting: home » products » Mycream Men » composition » caffeine (Pag. 1) » caffeine (Pag. 2)
Caffeine - Pag. 2

Mycream Men:

Caffeina: natural ingredient of Mycream Men

Why do the caffeine in Mycream for Men

Caffeine is the alkaloid substance contained in coffee beans. It is very similar to theobromine, the alkaloid substance contained in chocolate and theophylline, the alkaloid of tea leaves.
These three alkaloids widespread in the vegetable world, are called xanthines that have a molecular structure derived from xanthine. The term derives from the greek Xanthos, which means yellow. Caffeine, theobromine and theophylli-
ne are xanthines connected to methyl groups and thus are called methyl-xanthines.

Caffeine is 1,3,7-trimethyl-xanthine, theobromine is 3.7-dimethyl-xanthine, theophylline is 1,3-dimethyl-xanthine. Caffeine is very soluble in water, alcohol, ether and in acetone. It is very soluble in chloroform, ethyl acetate and tetrahydrofuran. In aqueous suspension has a neutral pH, its crystals are white, odorless, with bitter taste and have a melting point between 234 and 239°C.

Absorption, distribution, metabolism and elimination of caffeine

Caffeine is present in Mycream UomoThe caffeine is well absorbed orally, with a peak plasma grea-
ter after 120 minutes. It is able to distribute quickly on all tissues by crossing the blood brain barrier and the placenta. May be present in breast milk and therefore should be adopted special precautions for use during pregnancy and lactation.

The assumption of 100 mg. of caffeine leads to plasma concentrations between 1.5 and 1.8 mg / ml. The elimination of caffeine from the body is accomplished after hepatic metabolism with production of acid 1-metilurico, 1-7-methyl-
xanthine and metilaxantina. About 10% is always removed by the kidneys as unchanged caffeine.

The more responsible for the metabolism of caffeine is the whole of the enzyme cytochrome P-450 A2 which liver cells are particularly gifted. The half-life of caffeine is 2.5 - 4.5 hours in adults and extends substantially in the newborn baby by reason of his immaturity enzymatic system.

Various reasons may still influence the half-life of the molecule, including the condition of pregnancy. Do not forget, moreover, that the assumption of alcohol or medicines such as contraceptives, cimetidine, allopurinol and disulfiram protrude to extend it, while the smoking shortens as it urges the hepatic metabolism.

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