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you are visiting: home » products » Humor » against anxiety and depression » composition » st. john’s wort (Pag. 1) » st. john’s wort (Pag. 3)
St. John’s W. - Pag. 4


St. John’s Wort: natural ingredient of Humor

Pharmacological activities (To be continued ...)

As often happens for the active ingredients of natural origin, the result is given by the synergic action of all constituents existing in Humor, though certainly there is a prevalence of someone over the other.
Multiple pharmacological and clinical studies carried out on the plantdemonstrate that St. John’s wort is a plant safe, but it may have some contraindications such as photosensitivity during exposure to sunlight so that, during the period of assimilation is good to avoid exposure to the sun and / or tanning lamps. Must not be used St. John’s wort during pregnancy and lactation.

St. John’s Wort: natural ingredient of HumorAt therapeutic doses there is no inhibition of MAO (Inhibitors of Mono-Amino-Oxidase, raise the plasma levels of serotonin, nore-
pinephrine and dopamine by inhibiting the mono-amino-oxida-
se enzymes that reduce, through a process of oxidation, the concentration blood of these neurotransmitters), even if the hypericin inhibits in vitro.

It is reported by some authors a certain hypotensive action. Not recommended for use during pregnancy, in the absence of specific studies. Are possible photosensitivity reactions and interference with antiretroviral drugs for HIV.
St. John’s Wort can interfere with the metabolism of carbamazepine, quinidine, calcium channel blockers, losartan, steroids, tamoxifen, taxol, digoxin, theophylline, cliclosporina, progestogens, warfarin, fenitorina, tolbutami-
de, digoxin.

Hormonal effects

In particular, it determines a discrete increase in nocturnal production of melatonin. This action promotes restful sleep and a better awakening without disturbing the sleep REM (rapid eye movement) that occurs during a stage of sleep during which the revision occurs and the record of events of the day.

Modulation of the liberation of cytokines

The extract of St. John's wort reduces the formation of interleukin-6 capable of sustaining the release of corticotropin, which is why often connected to depressive manifestations. Outcome calming nervous anxiety and relaxation placed in relation to the intervention of bioflavono-
ids, hyperforin, procyanidins.

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