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you are visiting: home » products » Humor » against anxiety and depression » composition » st. john’s wort (Pag. 1) » st. john’s wort (Pag. 2)
St. John’s W. - Pag. 2


St. John’s Wort: natural ingredient of Humor

Clinical uses

St. John’s Wort: natural ingredient of HumorThe antidepressant action of hyperi-
cum has been confirmed by multiple tests carried out by comparison with both placebo and with antidepressa-
nts known as sertraline, fluoxetine and the laparoxetine.
The results were so encouraging that in Germany, St. John’s wort has been approved by the pharmacopoeia as a method of treatment of anxiety and depression.

The effectiveness of hypericum is comparable to that of the imipramine emaprotiline. It was performed a meta-analysis of 23 randomized trials with hypericum which involved a total of 1757 patients with mild to moderate depression.
The conclusion was that the hypericum extract, assessed after 2-4 weeks is superior to placebo and as effective as traditional antidepressants.

The mechanism of action of Hypericum perforatum is that of inhibition of the reuptake of serotonin in the post-synaptic inhibition of the uptake of norepinephrine and dopamine and bond (in vitro) with the GABA receptor (GABA is the gama amino butyric acid and is an inhibitory neurotransmitter).

Pharmacological activities

St. John’s Wort is known in the medical field since the Middle Ages and in that time it was already used as an excellent remedy for the treatment of sleep disorders, anxiety, melancholy and restlessness. St. John’s Wort is also known for its soothing and anti-inflammatory characteristic so much so that its oil is still currently used for external use in burns or redness in various forms, are also attributed the quality hypotensive, antispasmodic and digestive.

It was called “St John’s wort” but on the derivation of this name there is more than one interpretation, that of Biblical derivation that wanted him as a food preferred by St. John or the more common from the fact that its beautiful yellow flowers sprouting in the summer, were collected in celebration of the festivities in honor of St. John. The proven interest from the scientific disciplines today is due to the increased possibility of use of standardized extracts of St. John’s wort in the treatment of states of modification of mood and also as a natural cure for depression mild and limited.

The extract of Hypericum perforatum in question in the present medicine and who is given the results of clinical research and pharmacological, is the extract titled to 0.3% in total hypericin, such as the one that is located in Humor. It is a total extract derived from the whole plant, the harvest of which is carried out during the flowering period and that is verified and guaranteed in active ingredient content.

Other properties attributable to hypericum are soothing in nocturnal enuresis, in mood changes during menopause, the seasonal depression and periods of nervous exhaustion. The virtues of hypericum are related to the plant complex is mainly represented by flavonoids such as hypericin. Among the many flavonoids recognized, can be found rutin, quercetin and hyperoside.

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