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you are visiting: home » products » E > Micra » composition » caffeine anhydrous (Pag. 1) » caffeine anhydrous (Pag. 2)
Caffeine A. - Pag. 2

E > Micra:

Caffeine Anhyd.: natural ingredient of E > Micra

Activities of caffeic acid

Recent studies on caffeic acid have highlighted the effect as responsible of the block of free radicals and a remarkable anti-inflammatory activity even when there uses in the form of ester. Esters of caffeic acid with betulinic acid, oleanolic acid and morolic (triterpene acids), have recently been discovered by German scientists in an extract of evening primrose (Oenthera biennis).

They showed that these esters, in vitro, have important results on cyclooxygenase 1 and 2 inhibitors and human elastase leucitaria. All protein compounds are the stud of inflammatory processes and have even indicated that their radical scavenging activity is able also to be beneficial to a normal consolidation of polyunsaturated fatty acids, typical of the plant itself.

Multiple studies have been conducted on the biological activities of chlorogenic acid. This acid strengthens and activates the immune system by stimulating the composition of interferon and possessing antimutagenic activity. A contemporary study has allowed us to connect the antimutagenic action of chlorogenic acid by blocking the composition of 8-hydroxydeoxyguanosine (8OHDG).

Examinations performed in vitro and in vivo to understand the mechanisms of DNA damage caused by oxygenated radicals produced by different agents, they found that the action of these agents, both external and internal, stimulates the formation of 8OHDG in DNA in vitro. The formation of 8OHDG can in fact be used as a marker to verify the DNA damage of cells by oxygenated free radicals and can be used to predict the importance carcinogen.

In model systems of lipid peroxidation, it was found that the composition of 8OHDG is prevented, inter alia, by a constituent purified from the fraction yellow ▀-carotinica, identified precisely as chlorogenic acid.

In continuation of these and other studies have also identified the mechanisms of repair of DNA damage by enzymes (glycosylase) that remove the individual nucleobases modified, preventing alterations in both stand-alone and provoked. In Japan, in 1994, were carried out further studies on the outcomes of some chemicals and active principles phenolic antioxidants, including caffeic acid and some of its derivatives in force in food plants.

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