MILK
THISTLE - Silybum marianum

Family: Asteraceae
Other names: Marian thistle,
St. Mary's thistle, Our Lady's thistle
Habitat: Native to the
Mediterranean region of Europe, southern Russia and
north Africa, but naturalized in California and the
eastern US. May be found growing wild in warm, dry
waste areas. Milk thistle may also be grown in gardens.
In Italy it is found mostly in the South and Center,
more rarely in the North. It is easily found in uncultivated
fields, pastures, along woodpaths.
It was chosen as an ingredient of Wonderup because:
It contains of a large number of bioflavonoid complexes
(phytoestrogens) called flavonolignans, including
principally silybin (of the sylimarin complex) accompanied
by isosilybin, dehydrosilybin, silydianin, silychristin,
etc. . These phytoestrogens, like those in the other
ingredients of Wonderup, regulate the production of
female hormones (estrogens), whose balance is fundamental
for the woman's general wellbeing and for a correct
and healthy development of the breast, the main receptor
of estrogens in the female body. A scarcely developed
breast is in fact the symptom of a lack of estrogens
during puberty, a lack which can be remedied by reestablishing
a correct level of estrogens through the delicate
and safe action of phytoestrogens, which feed the
female breast and restore its volume and tone.
Other characteristics
and properties:
Milk thistle was once greatly valued in folk medicine
in Europe - a reputation that has gradually unjustly
decreased. Milk thistle is in fact rich in therapeutic
virtues which make it precious especially in the treatment
of liver dysfunctions.
Milk Thistle has indeed a long history
of use in European folk medicine as a liver tonic. Silymarin
from Milk Thistle has shown a protective effect against
many types of chemical toxins, including alcohol. An
extract of Milk Thistle is used to improve liver function,
protect against liver damage and enhance regeneration
of damaged liver cells. Clinical studies have confirmed
the usefulness of standardized Milk Thistle extracts
in cases of toxic liver, cirrhosis, and other chronic
liver conditions secondary to alcohol abuse.
Properties and medical use of flavonolignans
(Silymarin) from Silybum marianum
Phytotherapy Research (United Kingdom), 1996, 10/SUPPL.
1 (S25-S26)
Purified flavonolignan extracts from the fruits of the
milk thistle (Silybum marianum (L.) Gaertn., syn. Carduus
marianus L.) mainly contain silymarin, an isomer mixture
of silibinin, isosilibinin, silicristin and silidianin.
Silymarin is used for oral treatment of toxic liver
damage (induced by alcohol, drugs or environmental toxins)
and for supportive therapy in chronic inflammatory liver
diseases and in liver cirrhosis. Silymarin and its main
isomer silibinin, respectively, have been shown to possess
antioxidant properties thus preventing lipid peroxidation
and membrane destruction in cells. In addition, protein
biosynthesis and cell regeneration are accelerated in
the damaged liver leading to restoration of the liver
functions. Certain mushroom toxins are prevented from
entering the liver cell by silibinin due to competitive
inhibition of receptors at the cell membrane. Intravenous
treatment with a soluble silibinin derivative is now
an important life-saving factor in the standard therapy
of cases of Amanita phalloides poisoning. Finally, it
has recently been shown that silymarin inhibits leukotriene
production which explains its antiinflammatory effect
and that it has an antifibrotic action. Clinical trials
confirm the positive effects found in experimental studies.
Thus, silymarin is nowadays not only the best documented
drug for liver therapy but also one of the most intensively
investigated plant extracts with known mechanisms of
action.
* Liver regenerative tonic - Helps with liver problems
or enlargement: alcoholic liver disease, drug-induced
liver disease, chronic hepatitis, liver cirrhosis, jaundice,
multiple chemical sensitivities, industrial toxin exposure,
detoxification/cleansing programs. Protects liver from
toxic mushroom poisoning. Regenerates liver tissue damaged
by hepatitis, cirrhosis, alcoholism, drugs, and environmental
toxins. Also helps with fatigue, depression, and food
allergies.
Milk Thistle prevents free radical
damage to liver cells, prevents the formation of leukotrienes
and stimulates the production of new liver cells (protein
synthesis or cell protein production), accelerating
regeneration process. The liver protects the body from
toxic chemicals. Silybin, found in Milk Thistle, protects
the liver from environmental toxins entering the body
through food, water, air and skin. Silybinin has no
known effects on the liver enzyme system; therefore,
it protects the body from damaging effects of pharmaceutical
drugs and anesthesia without breaking down drug delivery.
With all that the liver must process
in our daily lives, it is no wonder it may become overwhelmed
at times. Milk thistle can help rejuvenate it and possibly
even protect it from future damage. Anyone who has or
has had hepatitis, cirrhosis or other conditions of
the liver or gall bladder should consider adding milk
thistle to their supplement plan. In fact, it wouldn't
hurt everyone to add it as a tonic herb.
* Poisoning antidote - especially for
the Death Cap Mushroom.
Silibinin and other components of the silymarin complex
were first discovered to be beneficial in treating liver
diseases in Germany several decades ago. A favorite
national pastime in Germany is mushroom collecting,
a practice with inherent risks, such as Amanita phalloides
- the Death Cap mushroom. Consuming the Death Cap mushroom
results in severe, usually deadly, liver damage (it
destroys its cells) - in fact, those that survive Death
Cap poisoning have been so badly damaged that they most
often require liver transplants to survive. Miraculously,
silymarin binds to the liver cells preventing the mushroom
poisons from also binding, blocking their poisonous
effect. The silymarin is also able to directly neutralize
the poison itself, making it effective even though it
has been taken after the mushroom poison has been ingested.
Milk thistle extract, for this very reason, is kept
on hand in German hospitals where it is administered
on an emergency basis for treating otherwise fatal Death
Cap poisonings.
* cholagogue - affects liver and detoxification
systems due to its ability to stimulate the emptying
of the gallbladder and the flow of bile into the duodenum.
* acts as an antioxidant, with far
greater free radical damage control than vitamin E.
Silybin, found in Milk Thistle stimulates Super Oxide
Dismutase (SOD) activity which acts as free radical
scavenger more potent than Vitamin E (SOD is "a
metal-containing enzyme that reduces potentially harmful
free radicals of oxygen formed during normal metabolic
cell processes to oxygen and hydrogen peroxide"
- Webster dictionary). In the presence of Silibinin,
less glutathione ("a peptide C10H17N3O6S that contains
one amino-acid residue each of glutamic acid, cysteine,
and glycine, that occurs widely in plant and animal
tissues, and that plays an important role in biological
oxidation-reduction processes and as a coenzyme",
Webster) is used in the tissue, resulting in a smaller
decrease of the glutathione pool. Glutathione reduces
free radical activity, not only in the liver, but in
cells in the entire body. Milk Thistle inhibits the
enzyme, lipoxygenase, preventing the formation of leukotrienes,
components responsible for inflammations.
* galactogogue - stimulates milk production
in nursing mothers
* relieves cramps and mentrual pains
* treat headaches associated with menstrual
cycles
* balances female hormones (estrogens)
* demulcent effect in treating pleurisy.
* antihermorragic - known since ancient
times for this property
* depurative - purifies the blood and
the liver
* diuretic - facilitates elimination
of toxins through urine
* febrifuge - reduces fever
* appetite stimulant - aids digestion
- digestive bitter
* antispasmodic - prevents muscle cramps
Usage
Warnings
Mild laxative effect in some users. May cause loose
bowels for the first 2-3 days because of Gallbladder
stimulation, but this will subside.
Culinary uses:
Salad green & cooked vegetable (spinach like flavor)
* Formerly frequently cultivated in gardens
* The stalks may be eaten and are palatable and nutritious
* Young leaves may be eaten as a salad, and were sometimes
baked in pies
* The flower heads were formerly boiled and eaten, treated
like those of an Artichoke
Here is a plant that is truly a gift of nature being
both food and medicine. In the spring, the young shoots
can be boiled and eaten like cabbage and the young leaves
can be added to salads. In the fall, the seeds are a
favorite food of goldfinches and an important medicinal
for people. The flower heads were once boiled and eaten
like artichokes, according to Mrs. Grieve in her book
A Modern Herbal.
History and Curiosities
-- folk use:
* Thought to be a great breeder of milk and proper diet
for nursing women
* Thought to have a healing property in those with snake
bites
* If worn around the neck it would protect you from
snake bites
* Fruit formerly thought to cure hydrophobia
* Applied externally, said to have been proven beneficial
in cases of cancer
* The young, tender plant be boiled and eaten in the
spring as a blood cleanser
* Fruits have been used for many years for a variety
of conditions, especially liver complaints. However,
medicinal use of the plant, except as a simple bitter,
was practically discontinued early in the twentieth
century.
Pliney the 1st century ad Roman naturalist
stated the plant was excellent for carrying off the
bile, thus restoring liver function.
Was used by European wet nurses to
increase their breast milk.Ý The white veins
on the leaves represent drops of the Virgin Mary's milk
fallen there when she nursed the baby Jesus. Hence the
name marianum.
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